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pyrimidine

pyrimidine

1 9.0
A chemical building block of DNA and RNA with a ring of six atoms that includes two nitrogen atoms
  • noun
  • /pɪˈrɪməˌdin/
  • Specialized
: pirimidina
  • And since 2000, plant-killing compost has surfaced in more than a dozen states after the introduction of pyridine and pyrimidine carboxylic acids, persistent herbicides that do not break down during the composting process.
  • purines and pyrimidines

Examples

  • The thiophene ring in the 2-position of the pyrimidine core was shown to have little effect on the interaction of the compound with IN, and so this position was chosen for more dramatic changes influencing the physiochemical properties of inhibitors.

    Blog text (19)
  • There are pyrimidines, T&C and they just have a six membered ring.

  • All right, so pyrimidine synthesis, get my colors.

  • Soon the purine and pyrimidine rings nearly filled the screen.

    Fiction book (2000)
  • A pyrimidine carboxamide similar in structure to raltegravir was recently propelled into Phase II clinical trials by a separate group.

    Blog text (19)
  • The local chemical riff-raff—our soupy mix of adenosine, thymine, and all that collection of purines and pyrimidines—were determined to defend their home turf.

    Fiction book (1999)
  • In DNA, cytosine and thymine are pyrimidines, characterized by their single six-sided ring.

  • The new pyrimidine, which they named kappa, differs from the traditional pyrimidines in the orientation of its nitrogen atoms.

  • Without understanding the significance of his discovery, Chargaff reported that in DNA, the amounts of the purine adenine were roughly equal to the amounts of the pyrimidine thymine.

Surface Forms

pyrimidine singular
pyrimidines plural

Morphology

pyrimidine = pyrimidin + ine

A technical chemical name built from specialized combining forms (e.g. 'pyrimidin-') plus the suffix '-ine', so an average B1 learner cannot derive the meaning from familiar English components.

Etymology

Pyrimidine comes from an older chemical name pyridine plus the common ending -ine, and a helpful way to remember it is to notice the pyr- part (as in pyramid) which gives a short, clear image. Pyrimidines are the 'single-ring' building blocks of DNA and RNA, so the name helps you remember they are the smaller, one-ring bases compared with the two-ring purine bases.