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Glite Dictionary
pyrimethamine

pyrimethamine

1 9.7
A medicine used to treat infections caused by parasites such as malaria and toxoplasmosis
  • noun
  • /ˌpɪrɪˈmɛθəˌmiːn/
  • Specialized
translation icon : pirimetamina
  • In several regions, health officials recommend using pyrimethamine as part of the treatment for toxoplasmosis.
  • sulfadoxine/pyrimethamine
  • pyrimethamine plus amodiaquine
  • pyrimethamine plus artesunate

Examples

  • Over the entire at-risk observational period, use of **25;7000;TOOLONG plus amodiaquine reduced the subsequent rate of treatments by more than half compared with **25;7027;TOOLONG alone and by more than a third compared with sulfadoxine/pyrimethamine plus artesunate.

    Academic text (2002)

  • Another survey in the district of Kidal identified the mutation in 80% of cases and showed that no isolates carried the dhfr/dhps quintuple mutant (a genetic determinant of pyrimethamine resistance).

    Academic text (2014)

  • Systemic disease responds to sulfonamide and pyrimethamine.

    Academic text (2006)

  • Our results show that combinations of sulfadoxine/pyrimethamine plus amodiaquine and sulfadoxine/pyrimethamine plus artesunate were very effective after 14 days.

    Academic text (2002)

  • Our results show that combinations of sulfadoxine/pyrimethamine plus amodiaquine and sulfadoxine/pyrimethamine plus artesunate were very effective after 14 days.

    Academic text (2002)

  • The fixed combination of sulfadoxine and pyrimethamine has replaced chloroquine as the first-line therapy for uncomplicated falciparum malaria in several African countries.

    Academic text (2002)

  • 29 In Kampala, where resistance to chloroquine is very high, 16, 17 combining chloroquine with **25;7246;TOOLONG would be expected to offer little benefit over sulfadoxine/pyrimethamine.

    Academic text (2002)

  • Doctors often prescribe pyrimethamine to treat malaria in patients who show symptoms.

  • When dealing with certain parasitic infections, pyrimethamine is an essential component of the medical regimen.

Surface Forms

pyrimethamine singular
pyrimethamines plural

Etymology

The word pyrimethamine comes from two chemical parts: pyrimidine (a common ring found in many medicines) and amine ('a simple chemical group', like in 'amino'). So the name tells you it is a chemical drug, which helps you remember it as a medicine used against parasites such as malaria.