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presynaptic

presynaptic

1 7.7
On the sending side of a nerve cell before the gap between cells
  • adjective
  • /ˌpriːsɪˈnæptɪk/
  • Specialized
: presináptico
  • In chemical neurotransmission, the presynaptic neuron releases neurotransmitters into the synaptic cleft.
  • presynaptic function
  • presynaptic Ca2+ influx
  • presynaptic Ca2

Examples

  • The fact that we see considerable heterogeneity in the local presynaptic abundance of STIM1-RFP suggests that additional local factors may, in turn, control the localization of STIM1 in presynaptic terminals.

    Academic text (2016)
  • Based on the hypothesis that riluzole may be a presynaptic modulator of the glutamate transmission system, research activities have lately been directed at a possible effect of riluzole on motor neuron cells.

    Academic text (2000)
  • And because of that effect, it's called presynaptic inhibition.

  • And now we can understand that kind of a polymorphism in how much presynaptic glutamate gets released.

  • What you very often see is one of the neurotransmitters will exclusively work on a presynaptic autoreceptor.

  • And those receptors, some fraction of them are specific for the ligand that the presynaptic cell releases.

  • Synaptic delay means the time it takes for activation on the presynaptic side to reach the postsynaptic side.

  • We found the largest fraction of presynaptic cells in primary (7,723 ± 2,124 cells, or 25%) and secondary visual areas.

    Academic text (2017)
  • Presynaptic cells were mapped onto brain regions as defined by a mouse brain atlas (Franklin and Paxinos, 2012) (Figure 1C).

    Academic text (2017)
  • There are synaptic vesicles and a presynaptic darkly stained region of the cell membrane along the region of the outer hair cell involved in the synapse.

    Academic text (1998)

Surface Forms

presynaptic positive

Morphology

presynaptic = synaptic (semi-transparent) = pre + synapt + ic

Given knowledge of 'synaptic', the prefix 'pre-' straightforwardly adds the meaning 'before' or 'on the transmitting side before the gap'.

Etymology

Presynaptic breaks into pre- meaning 'before' and synapse, a word that means 'joining' and appears in words like synchronize where 'syn-' means 'together'. So presynaptic names the part of a nerve cell that comes 'before the joining' and sends the signal into the synapse.