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Glite Dictionary
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pileup

pileup

9.9
A view of many DNA reads at one position showing how often each DNA letter appears
  • noun
  • /ˈpaɪlˌʌp/
  • Specialized
translation icon : acumulación
  • The bioinformatics pipeline creates a textual pileup showing base counts and quality at each position.

Examples

  • The geneticist analyzed the pileup of data from the sequencing.

  • Researchers often use a pileup to identify mutations.

  • The sequencing data produced a clear pileup at chr7:142,345,900, enabling SNP calling.

  • During visual inspection, she noticed multiple pileups that suggested a high local sequencing depth.

  • The sequencing results generated a pileup of data at that genomic position, highlighting potential variants.

  • Researchers often look for a pileup of nucleotide calls to confirm the accuracy of their findings in genetic studies.

  • In bioinformatics, a pileup can indicate the level of confidence in detecting mutations at a specific site.

Synonyms

pile-up
vspileup
  • Specialized
1 9.9

Many particle collisions that overlap in a detector and make signals unclear

summarises aligned sequencing reads at one position to show variant evidence

Surface Forms

pileup singular
pileups plural

Morphology

pileup = pile + up (semi-transparent) = pile + up

Compositional 'pile' + 'up' but used as a technical metaphor in genomics for accumulated sequencing reads, requiring domain knowledge.

Etymology

Pileup comes from pile ('heap') and up ('together'), and the same picture works for data: many DNA reads or signals stack at one spot like coins in a pile. So a genetic pileup shows where information gathers and helps you find differences in the DNA.