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orthology

orthology

1 9.9
A relationship between genes in different species that come from the same gene in an ancestor
  • noun
  • /ɔrˈθɑlədʒi/
  • Specialized
: ortología
  • We reasoned that if these orthology-driven clusters represent real chromosomes, they should also cluster by linkage. Indeed, orthology-driven clusters A, B, C, and D were fully preserved in the linkage clusters.

Examples

  • Comparing gene orthologies revealed no particular patterns.

    Academic text (2017)
  • If any systematic bias is present in a fraction of the individual loci sampled, it is unlikely that, for example, a false grouping resulting from mistaken orthology would be reached repeatedly and consistently across the independently derived gene trees.

    Academic text (2010)
  • We reasoned that if these orthology-driven clusters represent real chromosomes, they should also cluster by linkage. Indeed, orthology-driven clusters A, B, C, and D were fully preserved in the linkage clusters.

    Academic text (2017)
  • Researchers examined the gene orthology to understand evolutionary relationships across species.

  • The study of orthology helps scientists identify genes that have similar functions in different organisms.

  • By analyzing gene orthology, biologists can trace the lineage of genetic traits between various species.

Surface Forms

orthology singular
orthologies plural

Morphology

orthology = ortho + logy

Although the form looks like the learned elements ortho- and -logy, the biological sense is a specialized technical term that an average learner would not be able to infer from the components.

Etymology

Orthology in biology comes from Greek parts ortho- meaning 'straight' or 'correct' and -logy meaning 'study', the same ortho- you see in orthodontist and orthodox. So in biology orthology is the study of genes that are the 'correct' matching genes across different species.