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nicotinamide adenine dinucleotide

nicotinamide adenine dinucleotide

8.3
A small molecule in cells that sends signals to control DNA repair and aging
  • noun
  • /ˌnɪkəˈtiːnəˌmaɪd ˌædəˈniːn daɪˈnʌkleəˌtaɪd/
  • Specialized
translation icon : dinucleótido de nicotinamida y adenina
  • Therapies that boost nicotinamide adenine dinucleotide may improve DNA repair and influence age-related diseases.

Examples

  • Recent studies show that nicotinamide adenine dinucleotide levels act as a signaling molecule regulating aging and metabolism.

  • Researchers measured nicotinamide adenine dinucleotide concentrations to test sirtuin activity in cultured human cells.

  • The nicotinamide adenine dinucleotide levels fluctuate in response to cellular stress.

  • Can nicotinamide adenine dinucleotide help with DNA repair?

  • Recent studies show that nicotinamide adenine dinucleotide levels act as a signaling molecule regulating aging and metabolism.

  • Researchers measured nicotinamide adenine dinucleotide concentrations to test sirtuin activity in cultured human cells.

  • Therapies that boost nicotinamide adenine dinucleotide may improve DNA repair and influence age-related diseases.

Synonyms

NAD
vsnicotinamide adenine dinucleotide
  • Specialized
7 7.5

A small molecule in cells that helps chemical reactions make energy

is also a signaling coenzyme regulating DNA repair and gene expression via enzymes

Surface Forms

Morphology

nicotinamide + adenine + dinucleotide

The term is a systematic chemical name: knowing 'nicotinamide', 'adenine' and 'dinucleotide' lets a learner infer it is a dinucleotide molecule containing nicotinamide and adenine units. However, the detailed biological role (coenzyme/signalling and regulation of DNA repair, gene expression, ageing) is specialist knowledge not predictable from the constituents, so the composition is clear but the functional meaning is only partially accessible.

Etymology

Nicotinamide adenine dinucleotide shows its parts: nicotinamide, adenine, and dinucleotide meaning two small blocks joined, so the name helps you remember it is a small molecule used in many cell tasks. Because of its parts and shape, it acts as a 'signal' that helps control DNA 'repair' and other processes linked to 'ageing'.