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nalidixic acid

nalidixic acid

7.2
An antibiotic that treats infections of the bladder and tubes that carry urine
  • noun
  • /nəˈlɪdɪksɪk ˈæsɪd/
  • Specialized
translation icon : ácido nalidíxico
  • Quinolones are synthetic derivatives of nalidixic acid, which was discovered during the purification of the antimalaria agent chloroquine.

Examples

  • In clinical trials, nalidixic acid has shown effectiveness against certain bacterial infections.

  • Seven reports were of animal studies; only one included any mention of ototoxicity, and it concerned mild inner ear toxicity that had been caused by nalidixic acid, which is a ciprofloxacin precursor.

    Academic text (2005)
  • Doctors often prescribe nalidixic acid to patients suffering from urinary tract infections.

  • After diagnosing her condition, the physician recommended nalidixic acid as the best treatment option for her urinary tract issue.

Synonyms

nitrofurantoin
vsnalidixic acid
  • Specialized
9.4

An antibiotic drug used to treat bladder infections

is used for urinary infections without stressing broad bacterial coverage
sulfamethoxazole
vsnalidixic acid
  • Specialized
8.0

A medicine that fights bacteria, used to treat urinary tract infections

is an antibacterial agent not described by specific drug group
sulfisoxazole
vsnalidixic acid
  • Specialized
8.1

A medicine that fights bacteria to treat infections like a bladder infection

is an antibacterial agent without naming the sulfonamide class
hexamine
vsnalidixic acid
  • Specialized
8.4

A medicine that prevents or treats infections in the bladder

is an antibacterial agent rather than a preventive antiseptic

Surface Forms

Morphology

nalidixic + acid

The form follows the productive 'X acid' naming pattern so a learner who knows 'acid' can infer this is a chemical substance (an acid). However, 'nalidixic' is a specific, non-decomposable chemical name and its antibacterial/medical function cannot be derived from the constituents, so the meaning is only partially predictable.

Etymology

Nalidixic acid gets its name from the way chemists name new chemicals: the first part nalidixic comes from old chemical name parts and the second part acid shows it is a chemical. It was one of the first medicines of its kind, so the name now refers to a drug 'used to kill bacteria', especially for 'urinary tract' infections.