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metacyclic

metacyclic

9.9
A life stage of some parasites that can infect a new host
  • adjective
  • /ˌmɛtəˈsaɪklɪk/
  • Specialized
: metacíclico
  • The metacyclic forms of the parasite are crucial for infection in new hosts.
  • metacyclic trypomastigotes

Examples

  • T. cruzi is transmitted to humans primarily through the infected feces of triatomine bugs that contain metacyclic trypomastigotes (vectorial transmission).

    Academic text (2013)
  • A further consideration to account for the relative lack of infections transmitted through breastfeeding is that, if they occur at all, blood-form trypomastigotes would be expected to occur in human milk and not metacyclic trypomastigotes, which are found in the vector.

    Academic text (2013)
  • Blood, metacyclic, and culture trypomastigotes are similar in form and structure, but the different forms may have different surface glycoproteins, which are used for cell invasion (17, 37).

    Academic text (2013)
  • Transmission of T. cruzi by breast-feeding is possible in animal models, but oral infections may be difficult to establish unless metacyclic forms of the parasite are involved. # Studies in Humans #

    Academic text (2013)
  • Ingestion of food or drink contaminated with vector feces (containing metacyclic trypomastigotes) or crushed insects is the most likely mode of oral infection (36).

    Academic text (2013)
  • In studies, scientists focused on the metacyclic stage of the parasite's life cycle to understand its transmission.

  • To prevent disease, it is important to minimize exposure to metacyclic forms of certain parasites.

Surface Forms

metacyclic positive

Morphology

metacyclic = cyclic (opaque) = meta + cycle + ic

The term names a specialized parasite life-stage, so the meaning is not directly recoverable from meta- + cyclic + -ic for an average learner.

Etymology

Metacyclic combines the parts meta- ('after' or 'beyond') and cyclic ('cycle' or 'stage'). A helpful way to remember it is 'the stage after other stages', and in parasites this often means the form that can infect a new host.