mesylate
- noun
- /ˈmɛsɪˌleɪt/
- Specialized
- In pharmaceutical formulations, imatinib mesylate is often preferred for its solubility and stability.
- imatinib mesylate
- effects of mesylate
- administered mesylate
Examples
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The imatinib mesylate groups in our study demonstrated a 50% decrease in intimal thickening and showed histological decreases in SMC migration.
Academic text (2012) -
Therefore, we conclude that imatinib mesylate exhibits vasculoprotective properties during the early stages of arterial thrombosis.
Academic text (2012) -
The x2 test was used to evaluate statistical differences in morphometric data between the imatinib mesylate and control groups.
Academic text (2012) -
Statistical analysis of paired data (imatinib mesylate and control) was performed using the Wilcoxon signed rank test.
Academic text (2012) -
SMC inhibition is known to occur at imatinib mesylate concentrations of 0.5 M to 10 M.
Academic text (2012) -
Side effects, including nausea, vomiting, and cytopenia, may be overcome by the development of local forms of imatinib mesylate.
Academic text (2012) -
Following anastomosis, imatinib mesylate was administered for one, three, and seven days, and the regression of intimal hyperplasia was recorded.
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In our study, 400 mg tablets of imatinib mesylate were dissolved in PBS and administered systemically.
Academic text (2012) -
In the present study, we showed that relatively low doses of imatinib mesylate (10 mg/kg twice per day) mitigate the deleterious side effects of the drug.
Academic text (2012) -
In the literature, imatinib mesylate therapy has been used by cardiovascular surgeons to reduce neointimal hyperplasia due to balloon-induced injuries.
Academic text (2012)
Surface Forms
Morphology
mesylate = methanesulfonic acid (opaque) = mesyl + ate
Formed from the technical combining form 'mesyl' (methanesulfonyl) plus the chemical suffix '-ate'; this structure and meaning are specialized and not guessable by general learners.
Etymology
Mesylate comes from the chemical group mesyl, which is short for methanesulfonyl, and the ending -ate meaning 'a salt or ester'. So a mesylate is the salt or ester made from methanesulfonic acid, which is why medicines are sometimes given as a mesylate to change their stability or absorption.