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macroglobulin

macroglobulin

9.2
A large protein in blood that helps the immune system and makes blood clot
  • noun
  • /ˌmækroʊˈɡlɒb.jʊ.lɪn/
  • Specialized
translation icon : macroglobulina
  • In patients with emphysema, bronchiectasis, and bronchial asthma, a2-macroglobulin (a2-M) concentration was significantly increased as compared to the control group.
  • a2-macroglobulin

Examples

  • Elevated macroglobulin levels are often a sign of inflammation in patients.

  • Doctors checked for macroglobulin concentrations in the plasma to determine the patient’s risk of bleeding.

  • Keywords: Antiprotease Status; Respiratory Disorders; a1-proteinase inhibitor; a2-macroglobulin; Antitryptic activity; Antielastase activity; Respiratory disorders

    Academic text (2007)
  • In the study, researchers measured the levels of macroglobulin in blood samples to assess immune response.

Synonyms

globulin
vsmacroglobulin
  • Specialized
4 8.1

A protein in blood, milk, or seeds that helps fight infection and carry substances

is one specific large member of that protein group often aiding clotting
immunoglobulin
vsmacroglobulin
  • Specialized
3 7.0

A protein made by the body that acts as an antibody to fight germs

is a bigger plasma protein and can also support clot formation
immune globulin
vsmacroglobulin
  • Specialized
1 5.3

Proteins that the body makes to help fight infections

is larger in size and often tied to clotting as well
gamma globulin
vsmacroglobulin
  • Specialized
1 7.6

Proteins in the blood that help the body fight infection

is a larger plasma protein that also helps blood clot
human gamma globulin
vsmacroglobulin
  • Specialized
4.9

A protein from human blood that helps the body fight infections

is larger and may also play a role in blood clotting
immune gamma globulin
vsmacroglobulin
  • Specialized
5.2

A blood protein made by the body to fight infections

is larger and sometimes involved in clotting as well
immunoglobulin G
vsmacroglobulin
  • Specialized
4.5

A protein in the blood that helps fight bacteria and viruses

is a larger plasma protein sometimes involved in clotting rather than common defence
serum globulin
vsmacroglobulin
  • Specialized
5.9

Proteins in the liquid part of blood that include most antibodies that help fight infection

is a single large plasma protein often linked to clotting functions
plasma protein
vsmacroglobulin
  • Specialized
3.8

A substance in the liquid part of blood, such as albumin or globulin

is a particular large protein among these, often with immune and clotting roles

How Big

macroglobulin
  • Specialized
9.2
globulin
  • Specialized
4 8.1

Surface Forms

macroglobulin singular

Morphology

macroglobulin = globulin (semi-transparent) = macro + globulin

The meaning is largely compositional from 'macro-' meaning large and 'globulin', but it is a technical scientific term rather than everyday vocabulary.

Etymology

The word macroglobulin comes from two parts: macro- from an old Greek word for 'large' and globulin from an old Latin word for 'round' or 'ball', like the word globe. So, think of a macroglobulin as a 'large round protein' in the blood, which fits its role in the immune system and in blood clotting.