ketal
- noun
- /ˈkiːtəl/
- Specialized
- In organic chemistry, a ketal can act as a protecting group for ketones during synthesis.
- ketal-protecting
- ketal protecting group
Examples
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The ketal protecting group is derived from a carefully selected enol ether to which the phenolic hydroxyl is added under acidic conditions (Scheme VI).
Academic text (2001) -
Most recently, our research efforts have been focused on a low-activation-energy chemically amplified resist based on ketal-protected poly(hydroxystyrene).
Academic text (2001) -
So it can form a hemi ketal by attacking the carbonyl.
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An initial rapid protonation of the ketal is followed by the reaction of the protonated species with water to form a hemiketal and an alcohol.
Academic text (2001) -
General mechanism for acid-catalyzed hydrolysis of a ketal, a functional group widely used as the basis for imaging in positive-tone CA resists.
Academic text (2001) -
An improved KRS resist discussed below, KRS-XE, is based on a novel ketal-protecting group that is also significantly less volatile than MOP 39.
Academic text (2001) -
This germanium-containing polymer, similar to 5 wt% Ge, was then successfully protected with a ketal protecting group to afford an imageable CA polymer matrix.
Academic text (2001) -
The reaction produced a stable ketal that helped prevent unwanted reactions in further steps.
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Many chemists utilize a ketal to safeguard sensitive functional groups in their compounds.
Surface Forms
Etymology
Ketal comes from ketone plus the ending -al, following the same pattern as acetal. It names the compound made when a ketone reacts with an alcohol, and that's why chemists use a ketal to 'protect' or 'hide' the ketone during other steps.
