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isosorbide

isosorbide

1 6.5
A medicine that prevents chest pain and treats some heart failure
  • noun
  • /ˌaɪsoʊˈsɔːrbaɪd/
  • Specialized
: isosorbida
  • Patients receiving both drugs received nadolol as above; then isosorbide mononitrate was added starting with 10 mg orally twice daily, which was increased to 20 mg unless hypotension or severe headache occurred.
  • isosorbide mononitrate
  • isosorbide dinitrate
  • isosorbide intracoronary

Examples

  • The combination of nadolol and isosorbide mononitrate is more effective than nadolol alone in preventing variceal bleeding in relatively well patients with cirrhosis.

    Academic text (1996)
  • Five patients had to be withdrawn from isosorbide mononitrate treatment because of severe headaches.

    Academic text (1996)
  • The probability of death was only slightly lowered by the addition of isosorbide mononitrate in this study because there were few deaths related to bleeding.

    Academic text (1996)
  • The cumulative risk of bleeding was lowered by more than 50% in the nadolol plus isosorbide mononitrate group.

    Academic text (1996)
  • In patients receiving isosorbide mononitrate, intolerable headache was also judged to be a side effect necessitating cessation of that drug.

    Academic text (1996)
  • Patients with side effects related to b-blockers continued with placebo or isosorbide mononitrate, according to randomization; patients with side effects related to isosorbide mononitrate continued on nadolol alone.

    Academic text (1996)
  • We aimed to test the effectiveness of isosorbide mononitrate as an adjunct to the beta-blocker nadolol in the prophylaxis of first variceal bleeding in these patients.

    Academic text (1996)
  • When the four cases of portal hypertensive gastropathy were combined with variceal bleeding, the risk of bleeding in patients allocated nadolol plus isosorbide mononitrate was also significantly lower than that of patients randomized to nadolol alone.

    Academic text (1996)
  • The doctor prescribed isosorbide to prevent the patient's chest pain from angina.

  • Patients often take isosorbide to manage symptoms of heart failure effectively.

Synonyms

Isordil
vsisosorbide
  • Specialized
1 8.7

A medicine used to treat chest pain from heart problems

is a generic medication that prevents chest pain and treats some heart failure

Surface Forms

isosorbide singular
isosorbides plural

Etymology

Isosorbide comes from the prefix iso- meaning 'same' and sorbitol, which is a 'sugar from fruit'. It is basically a changed form of that sugar used as a medicine to help blood flow in the heart, so isosorbide is used to prevent chest pain and treat heart failure.