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investigational

investigational

1 7.2
Relating to a new treatment or vaccine that is being tested in people
  • adjective
  • /ˌɪnvɛstɪˈɡeɪʃənl/
  • Specialized
translation icon : experimental
  • Three investigational agents under study are voriconazole, posaconazole, and ravuconazole.
  • investigational drugs
  • investigational agents
  • investigational devices

Examples

  • New investigational drugs and devices are commonly used in critically ill patients.

    Academic text (2007)
  • In one investigational trial of ofloxacin (800 mg a day) and pyrazinamide (1500 mg a day), ADRs occurred very commonly.

    Academic text (2007)
  • Approval for the study was obtained from the University of Kentucky's investigational review board.

    Academic text (2004)
  • The antiviral drugs tested included FDA-approved medications and investigational antiviral agents.

    Academic text (2013)
  • Before this approach becomes the new standard, more investigational double-blind studies must be performed to evaluate patient outcomes (Giannoudis).

    Academic text (2005)
  • A recent study surveyed out-of-pocket costs for investigational compounds, which are of course heavily weighted to first indications.

    Academic text (2016)
  • The targeted agents given to the experimental group in SHIVA were drugs approved for clinical use but outside their approved indications, while in our study we matched patients to investigational drugs available through clinical trials at our institution.

    Academic text (2018)
  • The replication of the H275Y-mutant virus and its WT counterpart were equally inhibited by investigational drugs DAS181 and favipiravir in cell culture.

    Academic text (2013)
  • In a clinical trial, researchers are now testing an investigational drug that could help patients with Alzheimer's disease.

  • The hospital received approval to begin a study involving an investigational treatment for multiple sclerosis.

Synonyms

experimental
vsinvestigational
223 4.7

Using tests or trials to check new ideas

is used for formal testing and study especially in science and medicine
exploratory
vsinvestigational
31 5.2

Done to find out more about something

has a stronger focus on formal testing in science and medicine
explorative
vsinvestigational
1 5.0

To find new information or ideas by trying things

is used mainly for systematic study and testing in medical or scientific work

How Experimental

preclinical
  • Specialized
1 6.3
investigational
  • Specialized
1 7.2
experimental
223 4.7
clinical
  • Specialized
196 4.2

Surface Forms

investigational positive

Morphology

investigational = investigation (semi-transparent) = investigat + ion + al

The form is built from 'investigation' plus '-al', but the specialized scientific and medical sense 'experimental or being tested' is less directly predictable for learners.

Etymology

Investigational comes from investigate, based on a Latin root meaning 'to follow a trace', like the word vestige. So an investigational treatment or test is one under study where researchers 'follow the traces' to see if it works.