intrathecal
1
9.9
- adjective
- /ˌɪntrəˈθiːkəl/
- Specialized
- Intrathecal chemotherapy may effectively clear leptomeningeal disease, and systemic chemotherapy with CNS penetration may augment this approach.
Examples
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The treatment is for spinal cord (intrathecal, in the subarachnoid space—deeper than epidural) injections.
Blog text (16) -
In addition, she received intrathecal liposomal cytarabine, but her course was complicated by arachnoiditis, requiring the intrathecal therapy to be held after three doses.
Blog text (17) -
In one published series of five patients, all patients received intrathecal therapy.
Blog text (17) -
In patients not responding, intrathecal or intraventricular vancomycin remains a reasonable option.
Academic text (1995) -
Four patients were treated with intrathecal methotrexate and cytarabine, while the other was treated with methotrexate alone.
Blog text (17) -
A myelogram is a radiograph of the spine after an intrathecal injection of a radiopaque water-soluble contrast medium.
Academic text (2005) -
Our patient achieved excellent disease control with systemic chemotherapy with HyperCVAD and intrathecal liposomal cytarabine.
Blog text (17) -
A cell-mediated immune response to ibuprofen has been found with increased intrathecal IgG and immune complex formation in the cerebrospinal fluid.
Academic text (1998) -
Intrathecal injections are often used to deliver medications directly into the space surrounding the spinal cord.
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The doctor explained that intrathecal therapy could help manage the patient's chronic pain effectively.
Synonyms
1
9.9
Inside the protective membrane around the brain or spinal cord called the dura mater
1
8.2
Inside the spine or its nerve cord
Surface Forms
Morphology
intrathecal = thecal (opaque) = intra + thecal
The prefix 'intra-' is clear, but 'thecal' is not a standalone English word, making the overall word opaque for learners.
Etymology
Intrathecal comes from intra- 'within' and theca 'sheath' or 'case'. So, intrathecal means placed inside the sheath around the spinal cord, into the space that holds the spinal fluid.