Skip to main content
interstitium

interstitium

9.9
Space or tissue between the cells inside an organ
  • noun
  • /ˌɪntərˈstɪʃiəm/
  • Specialized
translation icon : intersticio
  • With decreased permeability, less fluid was probably removed from the interstitium, thereby decreasing the rate of deformation (37).

Examples

  • In a healthy organ, the interstitium helps support the structure and function of tissues.

  • After the release of external pressure, some fluid moves into the tissue from the adjacent areas, but fluid cannot move directly out of the lymphatics into the interstitium.

    Academic text (1999)
  • With the application of pressure, some of the water in the interstitium is forced into the lymphatics and eventually into the central circulation.

    Academic text (1999)
  • In the lung, virions and virus-infected cells were limited to the interstitium.

    Academic text (1995)
  • The slower rate at which water returns to the interstitium may be partially caused by the structure of the lymphatics, which are in close proximity to other microvessels within the tissue (38).

    Academic text (1999)
  • In the lung, the control monkey had very heavy antigen-positive staining multifocally in the interstitium and alveolar septa, primarily oriented around terminal bronchioles.

    Academic text (1995)
  • Histologically, they are granulomatous lesions localized mainly in the endocardium, subendocardium, or perivascular regions of the myocardial interstitium.

    Academic text (2007)
  • When examined microscopically, the alveolar structure appeared to be intact, the pulmonary interstitium was not notably edematous, and there was no evidence of inflammatory cell infiltration in the sham-operated group.

    Academic text (2018)
  • The interstitium surrounding the cells in the lung plays a crucial role in gas exchange.

  • The fluid in the interstitium can affect how nutrients are delivered to the cells.

Synonyms

interstice
vsinterstitium
1 9.8

A small narrow space between things where dust or air can pass

applies to larger internal spaces or tissue areas within an organ
interspace
vsinterstitium
1 6.8

A space between two things

is specific to the internal space or tissue found inside an organ
interstitial tissue
vsinterstitium
  • Specialized
7.4

Soft material between the cells inside an organ that helps support it

is broader, meaning space or tissue between cells inside an organ
intercellular substance
vsinterstitium
  • Specialized
7.0

Material between cells that supports them

refers instead to the surrounding space or tissue area, not just material

Surface Forms

interstitium singular
interstitia plural

Morphology

interstitium = interstice (opaque) = inter + stit + ium

The term 'interstitium' is derived from 'interstice', but its specialized meaning in medical contexts is not transparent to learners.

Etymology

Interstitium comes from Latin parts inter- 'between' and -stitium, showing the idea of something that 'stands between', like the word station. So in the body it refers to the space or tissue that 'stands between' cells and parts inside an organ.