histone

Examples

• All

• In this light, the effects of DZNep on inhibition of histone methylation are not specifically restricted to EZH2.

  Academic text (2017)

• This curve will wrap around proteins called histones and form some sort of bead necklace.

• So any questions at all about histone Marks and decoding?

• Yeah, because sirtuins are histone deacetylases, right?

• Among the histone modifications associated with cancer, methylation of histone lysine residues has gained much importance in recent years.

  Academic text (2017)

• In multiple myeloma cells, the anti-carcinogenic properties of triptolide have been shown to be mediated by the regulation of histone methylation.

  Academic text (2017)

• Deregulation of this histone modification can lead to epigenetic silencing of tumor suppressor genes, thus leading to tumorigenesis.

  Academic text (2017)

• There is an inverse correlation between EZH2 and class I histone deacetylases (HDACs) with TIMP-3 expression in breast cancer cells.

  Academic text (2017)

• Polycomb repressive complex 2 (PRC2) is one such methyltransferase that methylates lysine-27 of histone H3 (H3-K27).

  Academic text (2017)

• Histones are essential proteins in cell nuclei that help package histone into a compact structure.

Compounds

C

core histone

• Specialized

8.3

A protein that DNA wraps around inside cells

L

linker histone

• Specialized

7.5

A protein that helps fold and hold DNA inside the cell nucleus

Surface Forms

Etymology