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histocompatibility

histocompatibility

1 9.9
How well one person's cells match another's so the body does not reject a transplant
  • noun
  • /ˌhɪstəʊkəmˌpætəˈbɪlɪti/
  • Specialized
translation icon : histocompatibilidad
  • Major histocompatibility complex (MHC) class I antigens have a crucial role in the defense of an organism against intracellular pathogens and perhaps also against tumors.
  • histocompatibility complex
  • major histocompatibility

Examples

  • If you look at perfume, if I were to ask each of you to smell four different perfumes and then have you tell me which of the four is most attractive to you, it turns out that what drives that preference is its congruity with something called the major histocompatibility complex.

    Academic text (2013)
  • It is risky, but an unrelated donor can be found based on H.L.B. and D.R. histocompatibility.

  • * Immunology, Histocompatibility and Immunogenetics

    Academic text (2012)
  • Nobody's found that the HY histocompatibility antigens go goes through it.

  • "I specialize in the major histocompatibility complex (MHC) antigens," says Lunney.

    Academic text (1995)
  • They preferred the scent of a man whose major histocompatibility complex (MHC)—a series of genes involved

    Blog text (14)
  • First, DCs present T cells with their cognate peptide antigens in the context of the major histocompatibility complex (MHC).

    Academic text (2016)
  • A new study reinforces the finding that a region of the genome involved in immune system function, called the major histocompatibility complex (MHC), is involved in the genetic susceptibility to schizophrenia.

    Blog text (8)
  • Intracellular ACE is likely to be active during trafficking through the endoplasmic reticulum, as ACE has been shown to modify major histocompatibility complex (MHC) class I peptides in this compartment.

    Academic text (2018)
  • The major histocompatibility complex is crucial for ensuring that transplanted organs are not rejected by the recipient's immune system.

Synonyms

compatibility
vshistocompatibility
29 4.0

The ability of two things to work together without problems

is specific to cells or tissues matching for transplant to prevent immune rejection

Antonyms

histoincompatibility
  • Specialized
9.9

A mismatch between donor and receiver tissues that causes transplant rejection

Compounds

9.9

A group of genes that make cell-surface proteins telling the immune system if a donated organ is accepted

How Compatible

histocompatibility
  • Specialized
1 9.9
histoincompatibility
  • Specialized
9.9

Surface Forms

Morphology

histocompatibility = histocompatible (semi-transparent) = histo + compatible + ity

The formation is regular (histocompatible + -ity), but the combining form 'histo-' is technical and may be unfamiliar to average learners.

Etymology

Histocompatibility comes from histo- meaning 'tissue' and compatibility meaning 'able to live together'. So, histocompatibility is a way to say whether tissues from two people can 'live together' in one body without being rejected, which is why it matters for transplants.