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haptoglobin

haptoglobin

1 9.9
A blood protein that binds free hemoglobin and helps remove it
  • noun
  • /ˌhæp.təˈɡloʊ.bɪn/
  • Specialized
: haptoglobina
  • When free hemoglobin is present, haptoglobin helps clear it from circulation.
  • serum haptoglobin
  • haptoglobin and fibrinogen

Examples

  • When hemoglobin levels exceed the binding capacity of haptoglobin, the serum will become red or brownish, and hemoglobin will also be released into the urine.

    Blog text (9)
  • Humans are the only species with a modified form of haptoglobin, programmed by a gene acquired after human predecessors, Australopithecus, diverged from "Pan" apes.

    Blog text (12)
  • Hemoglobin is normally retained in the serum by binding to a specific protein called haptoglobin.

    Blog text (9)
  • Ordinarily, haptoglobin is responsible for "cleaning up" free hemoglobin in the bloodstream.

    Blog text (12)
  • The functions of this protein are distinct from haptoglobin's role in hemoglobin scavenging.

    Blog text (12)
  • Hemoglobin is contained within red blood cells, but when damaged, free hemoglobin is released, which is toxic; haptoglobin then "cleans" up the hemoglobin for disposal.

    Blog text (12)
  • Among the issues he highlighted was the fact that Homo sapiens have a gene that no other species possesses, a gene for a modified form of the protein haptoglobin.

    Blog text (12)
  • Moreover, significant differences have been encountered in acute phase response, and results showed a significant decrease in haptoglobin and fibrinogen in diseased newborn foals compared to controls.

    Academic text (2014)
  • LDH was 1249 IU/L, serum haptoglobin was less than 8 (normal 43-212 units), and ANA titer was positive at 1:80.

    Academic text (2007)
  • The haptoglobin protein binds free hemoglobin, aiding its removal from the bloodstream.

Surface Forms

haptoglobin singular
haptoglobins plural

Morphology

haptoglobin = globin (opaque) = hapto + globin

Both elements are technical combining forms used in biomedical terminology and their meanings are not derivable by an average B1 learner.

Etymology

Haptoglobin comes from Greek parts hapto- meaning 'to bind' and -globin as in hemoglobin meaning 'blood protein'. So haptoglobin is a protein that binds free hemoglobin in the blood, which is exactly its job.