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to glycosylate

to glycosylate

1 9.8
To attach a sugar to another chemical in living cells
  • verb
  • /ɡlaɪˈkɒsɪleɪt/
  • Specialized
: glicosilar
  • Health status was assessed using glycosylated hemoglobin (HbA1), a measure of the children's level of metabolic control.
  • glycosylated hemoglobin
  • glycosylated haemoglobin
  • glycosylated proteins

Examples

  • The enzyme's function is crucial because it can glycosylate the proteins, which impacts their activity and lifespan.

  • Serine can be phosphorylated or glycosylated and thereby can modulate the functional activity of the encoded protein.

    Academic text (1996)
  • The same study led to the identification of 28 STn-glycosylated proteins in the serum of gastric patients that were absent from healthy individuals.

    Academic text (2016)
  • In the present study, glycosylated hemoglobin (HbA1) was used to measure the degree of metabolic control for each child.

    Academic text (1990)
  • Glycomic studies are of key importance for the identification of abnormally glycosylated proteins and for precise glycosite assignment.

    Academic text (2016)
  • A1C was measured using the Bio-Rad DIAMAT glycosylated hemoglobin analyzer system.

    Academic text (2016)
  • In fact, glycosylated epitopes are widely used in clinical practice as non-invasive biomarkers for gastrointestinal cancer diagnosis and for monitoring disease progression.

    Academic text (2016)
  • Mrs. Brown's diabetes was well controlled, and her HbA1c (glycosylated haemoglobin) was 6.9%.

    Academic text (2011)
  • Researchers aim to glycosylate the therapeutic proteins to enhance their stability in the bloodstream.

  • During the experiment, we found that the bacteria could glycosylate various substrates effectively.

Surface Forms

glycosylate infinitive
glycosylated past participle
glycosylating present participle
glycosylates third person singular

Morphology

glycosylate = glycosyl (semi-transparent) = glycosyl + ate

The verb is formed by the regular addition of the productive verb-forming suffix '-ate' to the chemical noun 'glycosyl'.

Etymology

The word glycosylate comes from the Greek root glyco- meaning 'sweet' or 'sugar' and the ending -ate meaning 'to make', and the same glyco- appears in glucose, a common sugar. So to glycosylate is to 'make' something have a sugar part — to attach a sugar to another molecule, which is why scientists use the word for adding sugar to proteins or other compounds.