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Glite Dictionary
fibrinogen

fibrinogen

1 8.5
A protein in blood that helps form clots to stop bleeding
  • noun
  • /faɪˈbrɪnədʒən/
  • Specialized
translation icon : fibrinógeno
  • Concentrations of lipids, albumin, calcium, and phosphate in serum, and concentrations of fibrinogen and hemoglobin in plasma, were measured by standard methods in the clinical laboratory.
  • fibrinogen concentration
  • fibrinogen in plasma
  • serum fibrinogen

Examples

  • OCs induce increases in factor VII coagulant activity and in fibrinogen concentrations, and lower antithrombin concentrations.

    Academic text (1999)

  • Thromboelastography also allows dynamic monitoring of thrombus formation and abnormal conditions in platelet function, fibrinogen, and fibrinolysis.

    Academic text (2018)

  • That converts fibrinogen to fibrin and as a result, coagulation occurs.

  • Factor Ha (thrombin) turns fibrinogen into fibrin, and factor Xa turns prothrombin into thrombin.

    Academic text (2015)

  • One component contains fibrinogen, aprotinin, and/or factor XIII, and the other is made up of human thrombin dissolved in a calcium chloride solution.

    Academic text (2006)

  • As a result, fibrinogen adsorbs and converts in situ to fibrin through a structural cleavage and eventually creates thrombosis.

    Academic text (2018)

  • Screening tests for hypercoagulability included normal levels of serum fibrinogen, d-dimers, protein C and S, antithrombin III, but positive antiphospholipid antibodies.

    Academic text (2007)

  • Moreover, significant differences have been encountered in acute phase response, and results showed a significant decrease in haptoglobin and fibrinogen in diseased newborn foals compared to controls.

    Academic text (2014)

  • Considering the relative concentration as well as specific biological properties, albumin, fibrinogen, and fibronectin are the most probable proteins for adsorption on the surface of a biomaterial in contact with blood.

    Academic text (2018)

  • Fibrinogen is essential for blood clotting because it transforms into fibrin when a wound occurs.

Synonyms

factor I
vsfibrinogen
  • Specialized
8.1

A blood protein that becomes fibrin to help stop bleeding

is more specific about being soluble and forming insoluble fibrin in clotting

Surface Forms

fibrinogen singular
fibrinogens plural

Morphology

fibrinogen = fibrin (semi-transparent) = fibrin + ogen

The formation fibrin + -ogen (precursor/producer) is regular in biomedical terms but both morphemes are technical and not obvious to average B1 learners.

Etymology

Fibrinogen comes from fibrin, the same root as fiber, meaning 'thread', and the ending -gen, meaning 'to produce'. So fibrinogen is the protein in blood that produces the thread-like fibrin which helps form a clot to stop bleeding.