driver
1
8.6
- noun
- /ˈdraɪvər/
- Specialized
- In 2012, an extensive analysis of coding exons of 21,416 genes in 100 breast cancers identified novel driver genes, including CDKN1B153.
Examples
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However, only a limited number of these mutations give a selective advantage and might be considered driver mutations and not passenger changes.
Academic text (2017) -
In many cancers, specific mutations are recognized as drivers that lead to disease progression.
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So obesity is now the second most prevalent environmental driver of cancer.
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Mutations in oncogenes or tumor suppressor genes, and we call these mutations driver mutations.
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The research identified several genetic alterations that act as drivers of tumor growth.
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Scientists are studying how certain genetic changes serve as drivers in the development of cancer.
Compounds
- Specialized
4
6.8
A heavy machine that drives long posts into the ground for building foundations
- Specialized
2
3.9
A small program that lets a computer use hardware like a printer or keyboard
- Specialized
1
4.2
A computer program that helps the operating system talk to the screen or graphics card
- South African
1
9.1
A large tropical ant that moves in long lines and hunts other insects
- Archaic
An old-fashioned name for a person who writes for a living, often doing simple forms
- US
A brown wading bird like a small heron that lives in reeds and makes a loud booming call
How Influential
Surface Forms
Morphology
Etymology
Driver in medicine comes from the idea of 'drive' as 'to push forward', so a driver mutation is one that pushes cancer growth and helps the disease move ahead.