doxorubicin
2
9.9
- noun
- /ˌdɒksəˈruːbɪsɪn/
- Specialized
- Most recently, Zanon et al. suggested that despite the general ineffectiveness of chemotherapy, the most active drugs in the control of tumor growth in malignant schwannoma are decarbazine, doxorubicin, and ifosfamide.
- doxorubicin and cyclophosphamide
- doxorubicin, cisplatin
Examples
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Recently, several pharmacological agents, among them 4-phenylbutyrate and the anthracycline doxorubicin, have been reported to specifically increase the folding, trafficking, and functional cell-surface expression of DF508 CFTR.
Academic text (2001) -
Researchers are studying how doxorubicin can improve outcomes for patients with advanced leukemia.
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Doxorubicin has been shown to be the single most effective agent against these tumors.
Academic text (2001) -
The most commonly used chemotherapeutic agents include doxorubicin, cisplatin, and high-dose methotrexate.
Academic text (2006) -
Sorafenib, 5-fluorouracil, and doxorubicin are currently the standard treatment for systemic or locoregional disease, but have limited efficacy.
Academic text (2017) -
Due to the worsening of his KS lesions, he was enrolled in a clinical trial of liposomal doxorubicin (Doxil).
Academic text (1998) -
The nanoparticles targeted and entered HER2-positive tumor cells, and the release of doxorubicin was enhanced by glutathione (GSH), which is present at higher concentrations in cancer cells.
Academic text (2017) -
The child was started on multiagent chemotherapy with vincristine 1.4 mg/m², doxorubicin 50 mg/m², and cyclophosphamide 700 mg/m².
Academic text (2007) -
The doctor explained that doxorubicin is used in chemotherapy to treat various forms of cancer.
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Many patients have reported side effects after receiving doxorubicin as part of their treatment plan.
Surface Forms
Etymology
The word doxorubicin comes from the older drug name daunorubicin and the ending -rubicin, which points to the red color ('red') common to these drugs. So a helpful way to remember doxorubicin is as a red antibiotic used in chemotherapy, closely related to daunorubicin.