Skip to main content
cyclophosphamide

cyclophosphamide

7.4
A medicine that weakens the immune system to treat diseases where the body attacks itself and to prevent transplant rejection
  • noun
  • /ˌsaɪkloʊˈfɑːsfəmaɪd/
  • Specialized
translation icon : ciclófosfamida
  • On the other hand, I know that some rheumatologists are very careful when they prescribe methotrexate or cyclophosphamide for autoimmune inner ear disease, and they obtain consent after a fairly detailed discussion.
  • cyclophosphamide and azathioprine
  • cyclophosphamide and methotrexate
  • immunosuppressive cyclophosphamide

Examples

  • To prevent organ transplant rejection, many patients receive cyclophosphamide as part of their treatment plan.

  • Immunosuppression was induced in the animals via the administration of steroids and cyclophosphamide.

    Academic text (2008)
  • Cyclosporin is rapidly replacing azathioprine, chlorambucil, or cyclophosphamide as the supplementary agent of choice in patients of all ages, provided they have normal renal function.

    Academic text (1991)
  • Immunosuppressive agents have also been used, and these include: azathioprine, methotrexate, cyclophosphamide, gold, chlorambucil, and mycophenolate mofetil (reviewed in ref. 19).

    Academic text (2007)
  • Doctors often prescribe cyclophosphamide to help patients manage severe autoimmune diseases.

  • During the treatment of lupus, the doctor recommended cyclophosphamide to suppress the patient's immune response.

Synonyms

immunosuppressant
vscyclophosphamide
  • Specialized
1 6.1

A drug that weakens the body's immune system to stop it rejecting a new organ

is one specific medicine within that group
immunosuppressive drug
vscyclophosphamide
  • Specialized
1 3.9

A drug that makes the body's immune system weaker to prevent organ rejection or treat autoimmune disease

is the particular medicine used in those treatments
cytotoxic drug
vscyclophosphamide
  • Specialized
1 4.9

A medicine that kills cells and helps treat cancer during chemotherapy

focuses on lowering immune activity rather than direct cell killing
immunosuppressive
vscyclophosphamide
  • Specialized
6.7

A drug that lowers the body's natural defence to prevent organ rejection

is a single medicine that belongs to this drug class
immunosuppressor
vscyclophosphamide
  • Specialized
7.2

Drug that makes the body's immune system weaker

is a specific therapeutic example, not the general category

Surface Forms

Morphology

cyclophosphamide = phosphamide (opaque) = cyclo + phosphamide

Although analyzable as 'cyclo-' + 'phosphamide', the elements are specialised chemical combining forms and the meaning is not derivable for a typical B1 learner.

Etymology

The word cyclophosphamide is built from cyclo- meaning 'circle' (like cycle), phosph- for 'phosphorus', and -amide a chemical ending from 'ammonia'. So, the name shows it is a chemical medicine with a ring and phosphorus, which helps explain why it can slow the immune system and be used to treat autoimmune disease or prevent transplant rejection.