cholestasis
1
9.9
- noun
- /koʊlɛˈsteɪsɪs/
- Specialized
- Itching in normal-looking skin may be a presenting or prominent feature of systemic disease due to cholestasis, chronic renal disease, or adverse drug reactions.
Examples
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Clinical features include severe cholestasis and hypoprothrombinaemia, progressive hepatic failure, and death in most patients.
Academic text (1994) -
Overall, 22 (76%) developed symptoms of PBC and 24 (83%) had liver function tests persistently showing cholestasis.
Academic text (1997) -
Endogenous opioids have been implicated in the production of pruritus due to cholestasis.
Academic text (1996) -
The second or biliary stage usually presents with intermittent right upper quadrant pain with or without cholangitis or cholestasis.
Academic text (2007) -
Orlistat is contraindicated in patients with chronic malabsorption syndrome or cholestasis and in women who are pregnant or breastfeeding.
Academic text (2012) -
When patients presented with cholangitis, jaundice, or a flu-like syndrome and cholestasis, ERCP was done to confirm obstruction of the endoprosthesis.
Academic text (1992) -
Cholestasis can lead to symptoms like jaundice and severe itching due to the buildup of bile in the liver.
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Doctors diagnosed her with cholestasis after she reported persistent itching and changes in her skin color.
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The patient experienced cholestasis, which made it difficult for his body to process nutrients from food due to blocked bile flow.
Synonyms
Very little or no bile flows into the intestine, making the skin and eyes yellow and stools pale
How Much
Surface Forms
Morphology
cholestasis = chole + stasis
The term is a medical compound derived from Greek, not transparent to English speakers without specialized knowledge.
Etymology
Cholestasis comes from the Greek parts chole meaning 'bile' and stasis meaning 'standing still'. So, cholestasis is like bile 'standing still', which is why it means a reduced or blocked flow of bile from the liver.