chelator
- noun
- /ˈkiːleɪtər/
- Specialized
- There is a certain paradox in that gentamicin exerts its toxic actions as an iron chelator while other chelators are protective.
- iron chelators
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Watch on YouTubeSo many bacteria use non ribosomal peptide synthesis machinery in order to make chelators in order to acquire iron.
- So many bacteria use non ribosomal peptide synthesis machinery in order to make chelators in order to acquire iron.
Examples
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So many bacteria use non ribosomal peptide synthesis machinery in order to make chelators in order to acquire iron.
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Of course, it seems unlikely that the chelators are particularly good anticoagulants.
Blog text (25) -
And part of the reason that it is such an awesome metal chelator is because of entropy.
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Recent evidence that gentamicin may act as an iron chelator has resolved this paradox.
Academic text (1998) -
That's because certain chelators are known to have the side effect of acting as an anticoagulant.
Blog text (25) -
Iron chelators also hold the most promise for clinical intervention since they are already commonly used clinical agents in cases of iron overload.
Academic text (1998) -
Indeed, iron chelators were the most effective preventive agents in the guinea pig in vivo.
Academic text (1998) -
Alternatively, if aminoglycosides act as iron chelators, less toxic iron chelators could provide a more direct method of intervention.
Academic text (1998) -
Compelling evidence that this mechanism is part of the ototoxic actions of aminoglycosides comes from the success of iron chelators as antidotes in vivo.
Academic text (1998) -
Doctors often use a chelator to help remove toxic metals from the patient's body.
Surface Forms
Morphology
Etymology
Chelator comes from the Greek word chela meaning 'claw', and the chemistry word chelate pictures a molecule 'clawing on' to a metal ion. So a chelator is a substance that 'grabs' metal and helps remove it from a solution or the body.