bisphosphonate
1
7.6
- noun
- /bɪsˈfɑs.fəˌneɪt/
- Specialized
- In reviewing patient outcomes in the bisphosphonate therapy program, several patients experienced hypocalcaemia after the first zoledronic acid infusion.
- bisphosphonate therapy
- bisphosphonate drugs
- oral bisphosphonates
Examples
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Recently, there has been interest in the effect of bisphosphonates in localized disorders of bone, including avascular necrosis.
Academic text (2005) -
The analgesic effect of bisphosphonates appears to be dose dependent.
Academic text (2007) -
One drug should be enough, especially if bisphosphonate agents are used.
Academic text (2007) -
Medical treatment for this disease includes bisphosphonate and calcitonin therapy.
Academic text (2010) -
After 7 months on the bisphosphonate combination, the patient was already experiencing longer symptom-free periods.
Academic text (2008) -
Moreover, with the bisphosphonate drugs, one must instruct patients carefully about proper administration.
Academic text (2007) -
The main class of drugs is the bisphosphonates, with generic alendronic acid recommended as first-line treatment.
Academic text (2015) -
Furthermore, studies show additive effects on bone density when bisphosphonates are given after completing a therapeutic course with teriparatide.
Academic text (2007) -
Estrogens, selective estrogen receptor modulators, bisphosphonates, calcitonin, and even calcium and vitamin D all affect this site of action.
Academic text (2007) -
Doctors often prescribe bisphosphonate medications to help prevent bone loss in patients with osteoporosis.
Surface Forms
Morphology
bisphosphonate = phosphonate (semi-transparent) = bis + phosphonate
As a drug class name, 'bisphosphonate' is formed regularly from 'phosphonate' with the prefix 'bis-', but understanding requires medical or chemical background beyond average learners.
Etymology
Bisphosphonate comes from bis- 'two' as in bicycle and phosphonate, which is like phosphate, a part that sticks to minerals and bone. Think of it as having two 'phosphate' hands that cling to bone, so these medicines stay in bone and help slow bone loss and strengthen bones.