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apoptotic

apoptotic

1 8.4
Relating to the process when cells die on purpose
  • adjective
  • /ˌæpəʊˈptɒtɪk/
  • Specialized
translation icon : apoptótico
  • Caspases play an important role in apoptotic cell death.
  • apoptotic cells
  • apoptotic pathway
  • apoptotic cell death

Examples

  • We now understand a fair amount about apoptotic cell death.

    Academic text (2004)
  • Numerous apoptotic bodies were also noted.

    Academic text (2007)
  • Excessive apoptotic activity may result in unwanted cell death.

    Academic text (2012)
  • After 24 h, apoptotic cells were quantified as described elsewhere.

    Academic text (2000)
  • On the other hand, the inactivation of the apoptotic machinery is one of the key changes that allows cancerous cells to survive.

    Academic text (2001)
  • Too little apoptotic activity may result in an 'overgrowth' of unwanted cells, which may contribute to mutated cell growth and cancer.

    Academic text (2012)
  • In animal models, histologic findings resemble apoptotic cell death rather than necrosis.

    Academic text (2004)
  • In cases of aminoglycoside ototoxicity, it appears that the apoptotic cascade has been initiated.

    Academic text (2004)
  • Radical oxygen species and radical nitrogen species initiate the apoptotic cascade.

    Academic text (2004)
  • The drug was effective in inducing apoptotic cell death in cancerous tissues.

Surface Forms

apoptotic positive

Morphology

apoptotic = apoptosis (transparent) = apoptosis + ic

The adjective is a standard derivation from the noun 'apoptosis' using the productive suffix '-ic', yielding 'relating to apoptosis'.

Etymology

Apoptotic comes from apoptosis, made of the Greek parts apo- 'away' and -ptosis 'falling', so picture a leaf falling from a tree to help you remember it. So apoptotic describes cells that are 'falling away' on purpose, a controlled, programmed cell death that helps the body remove old or damaged cells.