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anergy

anergy

9.9
A weak immune reaction to a germ or test
  • noun
  • /ˈænərdʒi/
  • Specialized
translation icon : anergia
  • Individuals with a suspected tuberculous infection should be given a purified protein derivative (PPD) skin test with several controls to detect anergy.

Examples

  • If no skin response is noted for the anergy panel, the clinician must rely on other diagnostic tests to suggest the presence of a tuberculous infection.

    Academic text (1995)
  • Low doses lead to active suppression, whereas high doses result in anergy and/or deletion.

    Blog text (11)
  • Different mechanisms of tolerance are induced following oral antigen administration, including active suppression, clonal anergy, and deletion.

    Blog text (11)
  • Additionally, it has been shown that FoxP3 has an important role in the peripheral maintenance of nTreg phenotype stability, such as anergy and IL-2 dependence.

    Blog text (11)
  • Patients with autoimmune disorders may experience anergy, causing their bodies not to respond adequately to infections.

  • The doctor noted that the lack of reaction to the allergen indicated anergy in the patient’s immune system.

  • Due to anergy, the patient did not show any signs of an immune response during the test despite exposure to known allergens.

How Responsive

overreaction
27 4.9
immunocompetence
  • Specialized
8.1
anergy
  • Specialized
9.9
nonresponse
  • Specialized
7.2

Surface Forms

anergy singular
anergies plural

Morphology

anergy = energy (opaque) = an + energy

The established immunological sense ('absence of immune response') is a technical meaning that cannot be derived by an average learner from 'an-' + 'energy'.

Etymology

Anergy comes from the Greek parts a- meaning 'without' and ergon meaning 'work'. In medicine it describes the immune system 'not working' or not making a normal response to a germ, so anergy means a lack of immune reaction.