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amphotericin

amphotericin

1 8.6
A strong medicine used to treat serious infections caused by fungus or yeast in people with weak immune systems
  • noun
  • /ˌæmfəˈtɛrɪsɪn/
  • Specialized
: anfotericina
  • The patient was immediately started on Amphotericin B, 1 mg per kg per day.
  • amphotericin B
  • liposomal amphotericin
  • intravenous amphotericin

Examples

  • The lipid packaging places the amphotericin at the fungal cell, thus reducing the toxicity and allowing for larger doses.

    Academic text (2005)
  • As discussed, P. boydii is typically resistant to amphotericin B, so this patient received inadequate pharmacologic therapy.

    Academic text (2006)
  • Prednisone was discontinued, and the patient was started on amphotericin B.

    Academic text (2002)
  • But unlike Aspergillus, P. boydii is typically resistant to amphotericin B.

    Academic text (2006)
  • Use combination therapy to treat systemic infections; it may reduce the need for toxic doses of amphotericin B.

    Academic text (2005)
  • Following debridement, an induction phase of treatment with high doses of IV amphotericin B is generally initiated to achieve high drug concentrations.

    Academic text (2008)
  • The next day, intravenous amphotericin B at 1.5 mg/kg/day was started along with saline nasal irrigation.

    Academic text (2004)
  • Management typically requires extensive surgical debridement followed by long-term antifungal therapy, primarily with intravenous amphotericin B.

    Academic text (2008)
  • Amphotericin B exerts broad-spectrum coverage and remains the drug of choice for life-threatening invasive fungal infections.

    Academic text (2006)
  • The doctor prescribed amphotericin B to treat the patient's severe fungal infection.

Synonyms

antimycotic
vsamphotericin
  • Specialized
1 7.3

A medicine that kills or stops fungi that cause infections

is a particular drug used for severe fungal infections in immunocompromised patients
antimycotic agent
vsamphotericin
  • Specialized
1 6.2

A medicine that kills or stops the growth of fungus

is a specific antibiotic and antifungal used for serious yeast and fungal infections

Surface Forms

amphotericin singular
amphotericins plural

Etymology

Amphotericin comes from the Greek root ampho- meaning 'both' and the common medicine ending -icin. A helpful way to remember it is to think of an amphibian, an animal that lives in 'both' water and land: amphotericin is a drug that fights serious fungal infections and its name hints that it can act in more than one way against those infections.