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X-linked

X-linked

1 8.5
A gene or condition on the X chromosome
  • adjective
  • /ɛks lɪŋkt/
  • Specialized
translation icon : ligado al cromosoma X
  • X-linked conditions, such as X-linked hemophilia, primarily affect males because they inherit only one X chromosome.
  • X-linked recessive
  • X-linked deafness
  • X-linked syndrome

Examples

  • While few endorse selective abortion based purely on sex, this has been done for couples at risk for inheritable X-linked diseases.

    Academic text (2004)
  • If it's X linked, why is there a predominance in males?

  • The association between PG and X-linked mixed deafness syndrome has been recognized for many years.

    Academic text (2005)
  • In the absence of a family history of X-linked mixed deafness syndrome, surgeons may have difficulty determining if a patient is at risk preoperatively.

    Academic text (2005)
  • In our study, patient 3 had been incorrectly reported as radiographically normal despite the presence of CT abnormalities consistent with X-linked mixed deafness syndrome.

    Academic text (2005)
  • Dent's disease, as diagnosed in this case, is an X-linked form of proximal renal tubular disease; it commonly causes hypercalciuria, nephrocalcinosis, and eventually, renal failure.

    Academic text (1996)
  • He was reviewed at the age of 34 because other family members had been found to have Dent's disease (an X-linked form of proximal renal tubular disease).

    Academic text (1996)
  • This genetic trait is X-linked, meaning it is passed down through the X chromosome from mother to son.

  • Doctors explain that many X-linked disorders disproportionately impact males compared to females.

Synonyms

sex-linked
vsX-linked
  • Specialized
1 7.0

A trait that genes on a sex chromosome cause, often on the X chromosome

is limited to genes carried on a particular sex chromosome

How Sex-Linked

X-linked
  • Specialized
1 8.5
sex-linked
  • Specialized
1 7.0
autosomal
  • Specialized
2 7.5

Surface Forms

X-linked positive

Morphology

X-linked = linked (transparent) = X + link + ed

The structure is X- (the chromosome letter) + 'linked' (past participle of 'link'), so the meaning 'associated with the X chromosome' follows directly from the parts.

Etymology

The word X-linked breaks into two parts: X stands for the X chromosome, the part of your DNA that helps decide sex, and linked comes from link, meaning 'joined' or 'connected'. So an X-linked gene is a gene 'connected' to the X chromosome, which is why some conditions appear more often in men than in women.