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UGT

UGT

9.6
An enzyme in the liver that helps change and remove drugs from the body
  • noun
  • Specialized
: UGT
  • The UGT enzyme plays a crucial role in helping the liver process and eliminate drugs from the body.
  • UGT genes

Examples

  • Both intervals contained genes encoding detoxification enzymes, with Q1 encompassing two cytochrome P450 genes, and Q4, a set of 10 UGT genes.

    Academic text (2017)
  • However, it is known that individual UGT genes can act on a range of substrates (Tukey and Strassburg 2000), so any selection acting on Ugt86Dd could be due to one or more unknown compounds to which flies can be exposed in nature.

    Academic text (2017)
  • We carried out a similar experiment for the Q4 region, testing three overlapping deficiencies that individually delete 11-19 genes, including variable numbers of the UGT genes resident within Q4.

    Academic text (2017)
  • Researchers are studying how UGT enzymes can influence the metabolism of various medications.

  • Deficiencies in specific UGT enzymes may lead to an increased risk of drug toxicity.

Surface Forms

UGT singular
UGTs plural

Etymology

The UGT is a lab abbreviation for UDP-glucuronosyltransferase, a family of enzymes whose name shows they 'transfer' a small sugar part to drugs, making them easier for the body to remove. So, UGT enzymes help the body process and get rid of medicines.