Treg

Examples

• All

• The role of Treg cells in controlling type 2 immune responses, particularly at mucosal surfaces, has become more apparent, but much work remains.

  Academic text (2016)

• While the Treg cell-specific deletion of CTLA-4 leads to fatal lymphoproliferative disease, deletion of IL-10 in Treg cells instead leads to increased inflammation at barrier tissues.

  Academic text (2016)

• The details of Treg cell control of type 2 immunity have been a major question in the field.

  Academic text (2016)

• The role for Treg cells in RA has been established in both patients and animal models.

  Blog text (11)

• The recent work of Bacher et al. further expands on this notion that Treg cells are actively involved in the regulation of Th2 responses.

  Academic text (2016)

• Thus, artificial induction of CTLA-4 expression on RA Treg restores their suppressive capacity 119.

  Blog text (11)

• The expression of similar transcription factors between effector T cells and Treg cells is thought to lead to the expression of similar chemokine receptors, allowing colocalization and more effective regulation.

  Academic text (2016)

• Using novel techniques to enrich rare antigen-activated T cells, they were able to identify a robust pool of activated Treg cells that prevent Th2 responses to common inhaled allergens.

  Academic text (2016)

• IFN-Is likely also regulate Treg function indirectly by induction of downstream regulatory effectors, such as IDO, which, when inhibited, causes a loss of Treg suppression in many tumor types.

  Academic text (2017)

• Researchers found that Treg cells play a crucial role in preventing autoimmune diseases by helping to regulate the immune response.

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Etymology