CFTR
1
7.7
- noun
- /siː ɛf tiː ɑr/
- Specialized
:
CFTR
- Many researchers are studying the CFTR gene to find new treatments for cystic fibrosis.
- CFTR mutations
- CFTR expression
Examples
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So, despite not having cystic fibrosis, his parents are aware that he carries mutations in the CFTR gene.
Blog text (31) -
Mutations in the CFTR gene disrupt the balance of chloride ions in cells, leading to cystic fibrosis.
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One of their copies of the CFTR gene works well enough to do the job.
Blog text (32) -
For whatever reason, Colman had a genetic test including CFTR eleven years ago.
Blog text (31) -
CF is a genetic disease caused by mutations in a gene called the CFTR gene.
Blog text (32) -
There are over 1,500 documented mutations in the CFTR gene and counting.
Blog text (32) -
We're now looking for all the common polymorphisms of CFTR, the cystic fibrosis responsible gene.
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Instead, according to the SFGate article, Colman was found to have mutations in CFTR that could potentially cause CF.
Blog text (31) -
Now J.P. Clancy and colleagues report that gentamicin given to five patients for a week increased functional CFTR expression in the airway.
Academic text (2001) -
The CFTR gene is crucial for producing a protein that helps regulate salt and water movement across cell membranes.
Synonyms
A gene making a membrane protein that controls salt and water in lung cells and whose mutations cause cystic fibrosis
Surface Forms
Morphology
CFTR = C + F + T + R
CFTR is an initialism/acronym whose letter components do not convey morphological meaning to learners and the full sense depends on knowing the expanded phrase.
Etymology
CFTR comes from the four words Cystic Fibrosis, Transmembrane, Conductance, Regulator, and the name means it 'regulates' the 'flow' of chloride, a type of salt, 'across' the cell membrane. So, CFTR is the gene that makes the protein which controls chloride movement in cells, and when it is faulty it causes cystic fibrosis.