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CD8

CD8

2 8.1
A protein on the surface of certain immune cells that helps them find infected cells
  • noun
  • /siː diː eɪt/
  • Specialized
translation icon : CD8
  • CTLA4 blockade predominantly restrains T regulatory cells (Tregs) to increase the proportion of CD8+ T cells.
  • CD8 T cells
  • CD8 T cell counts

Examples

  • Of interest, median CMV-specific interferon-gamma CD8+ T-cell counts were comparable in D-/R and D+/R+ pairs (P = 0.470).

    Academic text (2018)
  • Enlargement of the salivary glands due to infiltration by CD8 lymphocytes is seen in both adult and pediatric HIV infection (figure 3).

    Academic text (2000)
  • The diagnosis of juvenile patch MF with CD8+ cells was made.

    Academic text (2007)
  • However, direct survival effects of IFN-I have also been reported on intratumoral CD8 T cells.

    Academic text (2017)
  • Lymphoproliferation mainly involved T cells negative for the CD4 and CD8 receptors.

    Academic text (2000)
  • However, it is suggested that CD8+ Tregs suppress target cells by both contact-dependent and contact-independent mechanisms.

    Blog text (11)
  • The patient also had a low CD4 (52 UL) and CD8 (92 UL) count.

    Academic text (2007)
  • Recent studies have reported the preferential activation of drug-specific CD8+ T cells in the pathophysiology of some bullous drug eruptions.

    Academic text (2007)
  • Although the diagnosis is often made clinically, histology shows infiltrates of perifollicular and intrafollicular CD4+ and/or CD8+ T-cells.

    Academic text (2007)
  • The activity of CD8 cells is crucial for recognizing and destroying infected or cancerous cells.

Synonyms

cluster of differentiation 8
vsCD8
  • Specialized
7.4

A protein on the surface of killer T cells that helps them find infected cells

is the short letter-number form used instead of the full name

Compounds

CD8 cell
  • Specialized
5.5

A type of white blood cell that finds and kills virus-infected or abnormal cells

CD8 T cell
  • Specialized
4.6

A kind of immune cell that finds and kills cells infected by viruses

Surface Forms

CD8 singular
CD8s plural

Etymology

The word CD8 is the name scientists gave to a protein on the surface of some immune cells, where the CD part stands for the label 'cluster of differentiation' and the 8 is the group number. So, CD8 is used as a marker to identify the cytotoxic, or 'killer', T cells that help the body fight infections.