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BCL

BCL

1 8.7
A cancer of B cells, the white blood cells that help the body fight infection
  • noun
  • Specialized
: linfoma de células B
  • Doctors often test for BCL as it can help determine the type of treatment needed for patients with B-cell lymphoma.
  • bcl-2 protein
  • bcl-2 expression
  • overexpression of bcl

Examples

  • Any cytoplasmic brown staining was accepted as being positive for Bcl-2.

    Academic text (2008)

  • Immunoreactivity for bcl-2 was semiquantitatively scored.

    Academic text (2008)

  • Expression of bcl-2 protein.

    Academic text (2008)

  • Seven of the 15 BSCC specimens exhibited no immunoreactivity with bcl-2.

    Academic text (2008)

  • Sarbia et al. found a strong expression of bcl-2 in a series of 23 BSCCs of the esophagus.

    Academic text (2008)

  • We found no significant difference between the two groups in the PCNA index or the frequency of bcl-2 overexpression, nor did we find any significant difference in survival.

    Academic text (2008)

  • Immunophenotyping confirmed that the lymphoid nodules were B cell in nature and that they were Bcl-2 and IgD-positive.

    Academic text (2006)

  • The overexpression of bcl-2 could provide a potential mechanism for the growth and subsequent overaccumulation of tumor cells in epithelial tissues.

    Academic text (2008)

  • The bcl-2 protein is a proto-oncogene that promotes oncogenesis by blocking programmed cell death (apoptosis).

    Academic text (2008)

  • The study indicated that the BCL protein plays a crucial role in preventing cell death in certain types of cancers.

Surface Forms

BCL singular
BCLs plural

Etymology

BCL stands for B-cell lymphoma. The B refers to B-cells, a kind of 'white blood cell', and 'lymphoma' means a 'cancer' of those cells, so BCL names this type of cancer.