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ALK

ALK

1 9.9
A gene and the protein it makes that is linked to some cancers
  • proper noun
  • Specialized
: ALK
  • Detection using the ALK-1 and CD30 antibodies is challenging.
  • ALK negative

We've got great a great drug called crizotinib for ALK positive lung cancer.

Examples

  • Moreover, a transcript involving ALK and the clathrin heavy chain genes was described in the pathogenesis of some IMTs. DNA ploidy analysis has been performed in some studies; it was initially done as a marker of neoplasia but may also be useful to determine prognosis.

    Academic text (2007)
  • Research shows that mutations in the ALK gene can lead to poor cancer prognosis.

  • So if you look at the highlights it says indication and usage is for ALK positive as detected by an FDA approved test.

  • Although ALCL in the rest of the body can be either ALK positive or ALK negative, the cases reported in the FDA study were ALK negative in 26 of 34 cases that reported this status.

    Academic text (2015)
  • Currently, 83 cases of ALCL have been reported worldwide, 82 of which were ALK negative.

    Academic text (2015)
  • Patients with ALK-negative cells appear to have a less aggressive outcome than those with ALK-positive cells. ALCL can occur in the skin as a primary cutaneous form, which is less aggressive and can be treated successfully with local radiation.

    Academic text (2015)
  • The Dolphin 7800 puts Honeywell in a strong position to capitalize on Android deployments within the enterprise," said Dan Popkin, vice president of business development of enterprise solutions at ALK Technologies.

    Blog text (33)
  • The ALK gene is often associated with specific types of cancer, guiding targeted therapies.

  • Patients diagnosed with ALK-positive lung cancer may respond well to certain treatments.

Surface Forms

ALK main

Etymology

ALK is an abbreviation of anaplastic, lymphoma, and kinase; anaplastic refers to a kind of cancer, lymphoma means a cancer of the lymph system, and kinase is a protein that acts like a 'switch' inside cells. So ALK names the gene and its protein, and when ALK changes it can help some cancers grow, which is why doctors test for it.